API#

Preprocessing#

Preprocessing utilities for multimodal single-cell data based on scanpy and muon

pp.preprocessing(mudata[, n_pcs_rna, ...])

Preprocess multimodal single-cell data stored in a MuData object.

Tools#

tl.PalantirExtension(mudata)

Trajectory inference using the Palantir algorithm on MuData objects.

tl.CellRankExtension(mudata)

Trajectory inference using the CellRank Pseudotime Kernel on MuData objects.

tl.pearson_correlation(mudata, key1, key2[, ...])

Compute the Pearson correlation coefficient between two variables stored in mudata.obs.

tl.spearman_correlation(mudata, key1, key2)

Compute the Spearman rank correlation between two variables stored in mudata.obs.

tl.fate_concentration_index(mudata[, ...])

Compute the correlation between fate concentration and pseudotime.

tl.terminal_pseudotime_enrichment(mudata[, ...])

Compute the average pseudotime enrichment across terminal states.

tl.terminal_state_silhouette(mudata[, ...])

Compute the silhouette score for terminal states.

Plotting#

pl.plot_tree(mudata[, embedding_key, ...])

Compute and visualize a principal tree from fate probabilities, using [FSKA22].

pl.plot_trends(mudata, ptf, gene[, ...])

Plot branch-specific dynamics of transcription factor expression and gene activity.

pl.plot_fate_probabilities(mudata[, ...])

Plot lineage fate probabilities on a low-dimensional embedding.

pl.plot_embedding(mudata[, embedding_key, ...])

Plot a low-dimensional embedding of cells colored by a given observation.